General Information

  • ID:  hor003679
  • Uniprot ID:  B0M3E4
  • Protein name:  CAPA-Periviscerokinin-1
  • Gene name:  NA
  • Organism:  Karoophasma botterkloofense (Gladiator) (Heel-walker)
  • Family:  Periviscerokinin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Karoophasma (genus), Austrophasmatidae (family), Mantophasmatodea (order), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  EAAGLIPFPRVG
  • Length:  12(1-12)
  • Propeptide:  EAAGLIPFPRVG
  • Signal peptide:  NA
  • Modification:  T12 Glycine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003679_AF2.pdbhor003679_ESM.pdb

Physical Information

Mass: 142283 Formula: C57H91N15O15
Absent amino acids: CDHKMNQSTWY Common amino acids: AGP
pI: 6.41 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 6
Hydrophobicity: 57.5 Boman Index: 63
Half-Life / Aliphatic Index: 1 hour Aliphatic Index: 105.83
Instability Index: 2550.83 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  22508719
  • Title:  Peptidomics-based phylogeny and biogeography of Mantophasmatodea (Hexapoda).